What is IVF?

Eggs are taken from the woman’s ovaries (or the eggs are taken from a donor) by surgery and then allowed to fertilise in a laboratory with sperm (from the woman's partner or, again, a donor), and then placed directly into the woman’s uterus by surgery. The woman is then made pregnant. The risk of then losing the pregnancy through early miscarriage is usually only the same as that of a couple conceiving naturally.

Who is IVF best suited to?

IVF is an option that women with unexplained fertility may like to go for. This is when tests on both the man and the woman in the couple have not produced any specific reason why trying for a baby naturally has not resulted in pregnancy.

Other women who may benefit from IVF as opposed to other forms of assisted conception included those who have blocked fallopian tubes (where the eggs are fine but are unable to make there way from the ovaries to be fertilised by the sperm).

Where treatments such as fertility drugs or IUI (Intrauterine insemination) have not been successful.

Is it possible to get IVF treatment on the NHS?

The National Institute for Clinical Excellence (NICE) have advised the Government that all couples where the woman is aged 23 to 39 years, who have an established caused of infertility or who have been trying to conceive without success for three years, should be allowed up to three cycles of IVF treatment on the NHS. However, the government only say that one cycle should be definitely free and that further cycles are a matter for individual health authorities.

It is possible to ‘go private’ and some clinics now offer good deals for certain patients who are willing to donate eggs. You can find out more about clinics near you and what to consider and expect from IVF treatment at the HFEA’s website, www.hfea.gov.uk

What are the alternatives to IVF?

Before you go for IVF treatment, it’s good to look at what the other options are. Your doctor will be able to explain these to you and advise you on what is a good option given your individual circumstances or specific fertility problem.

‘Assisted conception’ is when any means are used to help a woman conceive who is not able to or is having trouble getting pregnant just through sexual intercourse.

This can simply be giving the whole process a bit of a nudge or anything up to full-on medical involvement with the conception. Drugs will be used to help 'ripen' the eggs and make them more receptive to fertilisation.

Ovulation induction

This is used as a precursor to other courses of action like IVF but can be used on its own if the difficulty arises due to the woman's egg production.

The woman is prescribed clomiphene (or clomid) to take for a series of days each month in order to stimulate egg production.

Insemination

This
is when semen is gathered from the male and treated so that the sperm count is highly concentrated in the fluid which is then placed in the woman's uterus. This is quite non-invasive and is a useful method used when a man's sperm count is low. (That is, the semen he produces normally does not include a great number of motile or healthy sperm. It is possible to use a donor's sperm for this.)

ICSI (intra-cytoplasmic sperm injection)

ICSI is like IVF but here the sperm is actively injected into the eggs under laboratory conditions, rather than simply put together with the eggs, and they are left to fertilize. If the eggs are successfully fertlised through the ICSI process, they are placed into the uterus by surgery. ICSI is regarded by some doctors as preferable to IVF in instances where the male sperm is deemed to be particularly ‘subfertile’.

GIFT
(gamete intra-fallopian tube transfer)

GIFT is when the woman's eggs (one or possibly more) are taken from an ovary and a mixture of the egg and sperm is then placed directly into the fallopian tubes in the hope that fertilisation will occur. Unlike IVF, this process does require surgery under general anasthetic. When the eggs and sperm are left to fertilise in a laboratory, this process is called ZIFT (zygote intra-fallopian tube transfer). Both of these procedures will be carried out only if the fallopian tubes are found to be healthy and working effectively.

IUI (Intrauterine insemination)

This is when the sperm are sorted to ensure that the healthiest have been selected, and then that sperm is inserted directed into the womb at the point when the woman is most fertile. This procedure does not take very long and is preferred where the problems appears to be that the male has a low sperm count or if his sperm appears to have difficulty surviving the journey into the womb. This process may also be used where the woman is using a sperm donor.